Ep: Self-Brain Surgery: Rewiring Your Brain After Trauma with Christian Neurosurgeon Dr. Lee Warren
What if you have more influence over your thoughts, emotions, and healing than you realize? In this episode, I sit down with neurosurgeon, author, and podcast host Dr. Lee Warren to discuss the powerful connection between neuroscience, faith, and emotional healing.
We talk about how our thoughts literally change the structure of our brains, why trauma does not have to define our future, and how God has given us both the responsibility and the ability to participate in our healing. Whether you're struggling with anxiety, grief, people-pleasing, overthinking, or a painful season that feels impossible to move through, this conversation offers both practical hope and biblical encouragement.

WHAT YOU’LL LEARN
[00:00] Why You Have More Power Over Your Thoughts Than You Think
[04:00] What Self-Brain Surgery Is and Why It Matters
[07:00] Why Trauma Doesn't Have to Define Your Future
[10:00] The Connection Between Gratitude, Anxiety, and Brain Science
[17:00] Dr. Lee's Personal Story of PTSD, Grief, and Healing
[24:00] “Pick Up Your Mat and Walk”: God's Invitation to Participate in Your Healing
[28:00] How to Stop Participating in Your Own Demise
[33:00] Getting Better Instead of Bitter: How Suffering Can Refine You
[00:00] Why You Have More Power Over Your Thoughts Than You Think
When we're struggling emotionally, it's easy to feel powerless. Anxiety, fear, grief, and overwhelming emotions can convince us that we're stuck and that our thoughts are simply happening to us. But one of the most encouraging truths in this conversation is that God has given us far more influence over our thought life than we often realize.
While we can't control every circumstance that happens around us, we do have the ability to participate in how we respond to those circumstances and what we continually focus on. As Dr. Lee explains in this episode, both Scripture and neuroscience point to the same truth: our thoughts matter, and they have the power to shape both our brains and our lives.
[04:00] What Self-Brain Surgery Is and Why It Matters
Many of us have been taught that our brains are simply the result of our genetics, our personality, our childhood experiences, or our trauma. Dr. Lee challenges that idea by explaining the concept of neuroplasticity—the brain's ability to change and rewire itself throughout our lives.
While our experiences certainly shape us, they don't have to determine our future. We have the ability to create new pathways, new responses, and new patterns through what we repeatedly think about and focus on. That's what Dr. Lee calls “self-brain surgery”: partnering with God to intentionally reshape the way we think so our brains begin working for us instead of against us.
[07:00] Why Trauma Doesn't Have to Define Your Future
One of the most hopeful parts of this conversation is the reminder that trauma is not the final chapter of our story. Two people can experience the exact same painful event and have very different outcomes years later. The difference often isn't the event itself—it's how each person processes, responds to, and heals from that experience.
That doesn't minimize the pain of what happened. It simply reminds us that our future isn't determined solely by our circumstances. With God's help, healing, growth, and transformation remain possible. No matter what you've walked through, your story is still being written.
[10:00] The Connection Between Gratitude, Anxiety, and Brain Science
Dr. Lee shares fascinating neuroscience research showing how our brains respond differently depending on what we're focusing on. When we continually revisit fear, anxiety, or painful memories, certain parts of the brain become activated and our bodies respond accordingly. But when we intentionally focus on gratitude, hope, joy, and truth, entirely different neural pathways begin firing.
At the same time, this isn't about pretending hard things don't exist. Gratitude isn't denial. It's choosing to direct our attention toward what is still good and true, even while acknowledging what's difficult. It's a powerful reminder of Philippians 4 and the biblical invitation to dwell on what is true, noble, lovely, and praiseworthy.
[17:00] Dr. Lee's Personal Story of PTSD, Grief, and Healing
One of the most moving parts of this interview is hearing Dr. Lee's personal story. Years after serving as a neurosurgeon during the Iraq War, he unexpectedly found himself experiencing PTSD symptoms that had remained buried for years. What he thought he had moved past suddenly resurfaced in ways he couldn't ignore.
Later, he and his wife also experienced the unimaginable loss of their son. Through both trauma and grief, Dr. Lee shares how God met him in those painful places and showed him that suffering doesn't have to define a person forever. His story is a powerful reminder that healing is often a journey, not a single moment.
[24:00] “Pick Up Your Mat and Walk”: God's Invitation to Participate in Your Healing
One of my favorite moments in this conversation is when we discuss the story of the man at the pool in John 5. Jesus healed him, but He also invited him to participate in that healing by telling him to pick up his mat and walk.
There comes a point when God lovingly invites us to stop identifying ourselves by our pain and begin stepping into the healing He is offering. That doesn't mean the hurt wasn't real. It doesn't mean healing is easy. But it does mean we have a role to play in responding to God's invitation and taking the next faithful step forward.
[28:00] How to Stop Participating in Your Own Demise
One of Dr. Lee's most memorable statements is his first commandment of self-brain surgery: “I must relentlessly refuse to participate in my own demise.”
Many of us cope with stress, pain, and disappointment through habits that provide temporary relief but ultimately keep us stuck. Whether it's endless scrolling, overeating, overworking, numbing behaviors, or simply avoiding what needs to be addressed, those patterns often create more pain in the long run. Healing begins when we're willing to face what's difficult rather than continually escaping from it.
[33:00] Getting Better Instead of Bitter: How Suffering Can Refine You
As Dr. Lee reflects on his own experiences of loss and hardship, he shares a powerful perspective: suffering can either define us or refine us. While none of us would choose pain, God can use even the hardest seasons to deepen our faith, strengthen our character, and clarify what matters most.
One of the themes woven throughout this conversation is the choice between becoming bitter or becoming better. Healing doesn't mean the pain never happened. It means allowing God to redeem what was broken and use it to shape something beautiful in us. As Romans 5 reminds us, suffering can produce perseverance, character, and ultimately hope.
RESOURCES:
- The Life-Changing Art of Self-Brain Surgery by Dr. Lee Warren
RELATED EPISODES:
Ep 358: People Pleasing: Is This the Real Reason You're Exhausted + Overwhelmed?
Ep 359: When Emotions Feel Scary: Practical Tools to Courageously Process What's Inside
Ep 365: God Reveals So He Can Heal (And It's Time to Step Into That Healing)
